Ginseng leaves contain high saponin composition and content, but are used less often\nthan the root part. To develop a use for the leaves that exploits their properties, we studied ginseng\nleaves as the raw material of anti-aging cosmetics. This study highlights an assessment of the cellular\nfactivity and clinical efficacy of ginseng leaf extract, providing necessary information relevant to the\ndevelopment of new cosmetic products. Panax ginseng leaf purified extracts (PGLE) were shown\nto have high contents of Rb3 and Rb2. Rb3, the major chemical components of PGLE, promoted\ncollagen synthesis though the activation of transforming growth factor-�² (TGF-�²) in human skin\nfibroblast cells. In addition, the possibility of PGLE as an anti-skin-aging agent has also been clinically\nvalidated. Our analysis of the crowâ��s feet wrinkle showed that there was a decrease in the depth\nof deep furrows in the region of interest (RI) treated with PGLE lotion over an eight-week period.\nBased on these results, we suggest the possibility that PGLE, having high levels of Rb3, be considered\nas an attractive, wrinkle-reducing candidate for topical application.
Loading....